Independent category review · criteria published
Multivitamin for
GLP-1 users
A nutrient-coverage framework for reduced intake. We will name a winner only when enough labels can be verified.
Why multivitamin matters for GLP-1 users
In a study of adults on GLP-1 therapy, vitamin D deficiency was the most common nutrient abnormality found — present in 7.5% of patients at 6 months and 13.6% at 12 months.
Source and evidence
Metformin is frequently co-prescribed alongside GLP-1 therapy for type 2 diabetes, and long-term metformin use is associated with an increased risk of vitamin B12 deficiency.
Source and evidence
Scoring in progress — no confident #1 pick yet
Multivitamin: what to look for
- Vitamin D3 at or above 1000 IU per serving (deficiency is the most commonly documented gap in GLP-1 users)
- Methylated B vitamins (methylfolate, methylcobalamin) are NOT currently scored as a bonus — the evidence is contested outside a specific MTHFR subpopulation, so we don't reward it until independently verified
- Iron and calcium content is flagged, not scored — appropriateness is prescriber-dependent, not a universal positive or negative
- No mega-dose formulas (multiples of the RDA on fat-soluble vitamins) — more is not scored as better
OUR METHOD
How we ranked this
We score every multivitamin product the same way: how well-dosed it is against a clinical reference amount, whether the form is a good one, whether an independent lab has verified what's on the label, how clearly the label discloses every ingredient, and price per effective dose. On top of that, we add one GLP-1-specific check — for multivitamin, that means checking vitamin D3 is dosed adequately, since low vitamin D is the most commonly documented nutrient gap in people on a GLP-1 — and flagging, not scoring, iron and calcium, since the right amount of each depends on the individual. Every score is public and reproducible from the same two data sources anyone can check.
GOOD TO KNOW
Frequently asked
questions
- Best multivitamin for someone eating very little on Ozempic
- We haven't verified enough multivitamin products to name a confident #1 yet — no stockable brand in the NIH label database has cleared our bar. We publish scoring criteria (vitamin D3 adequacy, iron/calcium flagged not scored, no mega-dosing) and what we've scored so far instead of asserting a pick. Full methodology, axis weights, and changelog: /glp-1-supplements/methodology/.
- Do I need a multivitamin on a GLP-1? Which one?
- Not everyone does — reduced intake is the main driver of a real gap, and not everyone on a GLP-1 develops one. If you and your prescriber have identified a need, our criteria (not yet a confident #1 pick) are on the category page. Full methodology, axis weights, and changelog: /glp-1-supplements/methodology/.