A clearer daily stack,
built on evidence.

Search for the best supplements to take on a GLP-1 and you will get a great many confident lists. What you will not easily find is anyone telling you how they decided. That is not an accident. Almost every one of those lists earns a commission on the products it recommends, which makes the ranking and the revenue the same document. So let me be plain about ours before anything else. insyder.ai earns nothing. No commissions, no margins, no sponsorships, no affiliate links. Every product link goes straight to the brand, and we make nothing when you use it. What we have instead of a business model is a method, and the whole point of this video is that you should not take our word for a single ranking in it. You should be able to check it.

We take the published label data that supplement companies file with the National Institutes of Health, and we score products against a fixed, public methodology. Two thousand eight hundred and forty-seven products so far, across six categories. The scoring happens before we know anything about what we could sell, which is the part that matters. Every score carries what we call receipts — one line per axis explaining exactly why the product got the number it got. Not a star rating, not our impression, not a paragraph of adjectives. A dose in grams against a stated clinical floor. A certification with the listing URL. If you disagree with a score, you can open the methodology, open the label, and find the disagreement. That is the entire product.

GLP-1 medications work in part by slowing digestion and reducing how much you eat, and four fairly predictable consequences follow from that. First, rapid weight loss on a GLP-1 can include meaningful lean muscle, not just fat, and clinical guidance for this population recommends one point two to one point six grams of protein per kilogram of body weight daily to help preserve it. That is protein, and it is why protein is the first category. Second, and closely related, creatine monohydrate is the best-studied form for helping preserve strength during a weight-loss phase — though I want to flag now, and I will come back to it, that no trial has tested creatine specifically alongside a GLP-1. Third, these medications slow digestion, and soluble fiber like psyllium is the standard recommendation for supporting regular bowel habits when transit slows. And fourth, omega-3, which rounds out a cardiometabolic-support stack relevant to the same population many GLP-1 users fall into — adults managing weight or metabolic risk — on general, not GLP-1-specific, grounds. Four consequences, four categories. Nothing here treats or prevents anything, and none of it replaces a conversation with your prescriber.

Six axes. Dose against a clinical floor. Form, meaning whether the ingredient is the well-studied version. Third-party verification. Label transparency. Value per effective dose. And a GLP-1 tolerability overlay, which is where we account for things like sweeteners and format that matter more when your digestion is already slowed. Here is what a receipt looks like in practice, and it is worth seeing the difference. For the top creatine, the verification line reads: NSF Certified for Sport verified, with the listing URL, checked on the sixteenth of July. For almost everything else, it reads: no third-party seal found — checked NSF Certified for Sport, Informed Sport, Informed Choice, and USP. That second line is doing real work. It is not silence, and it is not an accusation. It tells you exactly which registries we searched and that the product was not in them. A missing seal is a fact about the search, and we say so.

Creatine first, because it is the clearest result in the entire data set. The highest-scoring creatine for GLP-1 users is BulkSupplements dot com Creatine Monohydrate, at one hundred and eight points — eight clear of second place, and one of only nine products out of two hundred and forty-six that carry a verifiable third-party seal. Five grams per serving against a three gram floor, in the reference-standard monohydrate form. Behind it, the same brand's capsule version and Pure Power's unflavoured monohydrate, both at one hundred, both also certified. Protein tells the same story at larger scale. Of one thousand one hundred and eighty-two protein products, only fourteen carry a third-party seal — and the top three are three of them. Ladder Whey Protein at ninety-eight, GHOST Whey at ninety-eight, and Klean Athlete Klean Casein at ninety-five. Twenty-six, twenty-five and twenty-four grams of protein per serving against a twenty gram floor. All three NSF Certified for Sport. When almost nothing in a category is certified, the few products that are will separate themselves. Fiber is where that breaks down, and it is worth sitting with. Of two hundred and twenty-eight fiber products, not one carries a third-party seal. Zero. So the ranking there rests entirely on dose and label transparency. Herbal Secrets Organic Whole Psyllium Husk leads at ninety-three, then Source Naturals at ninety-two, then Health Plus at ninety-two — and Health Plus is worth a look despite third place, because it carries seven grams of soluble fiber per serving against a five gram floor, the highest dose of the three. Omega-3: Source Oil Algae Omega-3 at eighty-five, with two thousand and twenty milligrams of EPA plus DHA per serving against a one thousand milligram floor, then the lemon-flavoured version of the same product, then Metagenics OmegaGenics at eighty-four.

Now the part that the affiliate lists leave out. There are no direct trials of creatine in people taking GLP-1 medications. None. We rank creatine because the muscle-preservation evidence in weight loss generally is good, and we say plainly on the page that the GLP-1-specific evidence does not exist. Two of our six categories — electrolytes and multivitamin — have no confident top three at all, because the products we would want to rank have no published label data in the NIH database. So those pages show you what to look for instead of pretending to a ranking we cannot support. And the verification axis is unforgiving on purpose: almost every product we score has no third-party seal, which is a genuine finding about this industry rather than a flaw in the method. If a category page ever looks thin, that is the method working. We would rather show you a gap than fill it with something plausible.

So: check us. The methodology is published, the scores are computed from label data anyone can pull, and every product card tells you plainly that we have no relationship with the brand and earn nothing if you buy. That is at insyder dot a-i. And whatever any ranking tells you, including ours — supplements are not necessary for everyone on a GLP-1. Confirm any addition with your prescriber, particularly if you take other medications.